Prepaid clinical development costs Prepaid Clinical Development Costs, Current Represents the amount of consideration paid in advance for clinical development that provides economic benefits within a future period of one year or the normal operating cycle, if longer. Award Timing Predetermined Award Timing Predetermined [Flag] Entity File Number Entity File Number Additional Paid-In Capital Additional Paid-in Capital [Member] Tabular List, Table Tabular List [Table Text Block] Recent Accounting Pronouncements New Accounting Pronouncements, Policy [Policy Text Block] Adjustment to Compensation: Adjustment to Compensation [Axis] Accrued Clinical Development Costs Accrued Clinical Development Costs [Policy Text Block] Disclosure of accounting policy for accrued clinical development costs. Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Equity compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Vesting of ESPP Shares (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Percentage of increase in royalty rate upon drawdown of third payment Percentage of Increase in Royalty Rate Upon Drawdown of Third Payment The percentage of increase in the Royalty Rate upon drawdown of the Third Payment. Total current income taxes Current Income Tax Expense (Benefit) Adjustment to Compensation, Amount Adjustment to Compensation Amount Risk percentage Concentration Risk, Percentage Debt discount and issuance costs Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net Credit Agreement Credit Agreement [Member] Credit Agreement Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Stock Options Common shares under option Share-Based Payment Arrangement, Option [Member] Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Percent Effective Income Tax Rate Reconciliation, Percent [Abstract] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Impairment losses Asset Impairment Charges Total stockholders' deficit Beginning balance Ending balance Equity, Attributable to Parent Debt Securities, Available-for-sale [Table] Debt Securities, Available-for-Sale [Table] Insider Trading Policies and Procedures [Line Items] Schedule of Property and Equipment Property, Plant and Equipment [Table Text Block] Common stock, shares authorized (in shares) Common Stock, Shares Authorized Issuance of common stock, net of issuance costs (in shares) Stock Issued During Period, Shares, New Issues Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Liabilities and stockholders' deficit Liabilities and Equity [Abstract] State State and Local Jurisdiction [Member] Aggregate Intrinsic Value Share Based Compensation Arrangement by Share Based Payment Award Aggregate Intrinsic Value [Abstract] Cover [Abstract] Cover [Abstract] Interests reverted to company Sale Of Future Royalties, Percentage Royalty Interests Reverted To Company Following Receipt Of Threshold Purchase Price Multiple Sale Of Future Royalties, Percentage Royalty Interests Reverted To Company Following Receipt Of Threshold Purchase Price Multiple Maximum Maximum [Member] Exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Pennsylvania PENNSYLVANIA Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Debt Instrument [Line Items] Debt Instrument [Line Items] Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Summary of Activity Relating to the Company's RSUs Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block] Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Retirement Benefits [Abstract] Retirement Benefits [Abstract] Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Proceeds from issuance of common stock, net of issuance costs Proceeds From Issuance Of Common Stock And Warrants Proceeds From Issuance Of Common Stock And Warrants Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Loss before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Entity Shell Company Entity Shell Company Sale of Future Royalties Sale of Future Royalties [Member] Sale of Future Royalties Schedule of Long-term Debt Instruments [Table] Schedule of Long-Term Debt Instruments [Table] Proceeds from issuance of convertible notes, net of issuance costs Proceeds from Issuance of Debt Effective annual imputed interest rate Sale Of Future Royalties, Effective Annual Imputed Interest Rate Sale Of Future Royalties, Effective Annual Imputed Interest Rate Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Stock based, amount capitalized Share-Based Payment Arrangement, Amount Capitalized Schedule of Income Taxes Paid Schedule of Cash Flow, Supplemental Disclosures [Table Text Block] Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Royalty Purchase Agreement Deferred Tax Asset, Royalty Purchase Agreement Deferred Tax Asset, Royalty Purchase Agreement Total amount of subsequent installment, subject to RIPA terms and conditions Amount of Subsequent Installment, Subject to Revenue Interest Purchase Agreement Terms and Conditions The total amount of the subsequent installment, subject to the terms and conditions of the Revenue Interest Purchase Agreement. Texas TEXAS Summary of Total Stock Based Compensation Expense Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Operating lease liabilities Operating lease liabilities (short-term) Operating Lease, Liability, Current Exercise of warrants (in shares) Stock Issued During Period, Shares, Warrant Exercises Stock Issued During Period, Shares, Warrant Exercises Software Software and Software Development Costs [Member] Consideration cash payment Future Up-Front Payment Future Up-Front Payment Document Fiscal Period Focus Document Fiscal Period Focus Intangible assets Intangible Assets, Net (Including Goodwill) Award Timing Method Award Timing Method [Text Block] Furniture, fixtures and other Furniture and Fixtures [Member] Award Type [Axis] Award Type [Axis] Collaborations with Third Parties Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Stock-Based Compensation Share-Based Payment Arrangement [Policy Text Block] Trading Symbol Trading Symbol 2029 Lessee, Operating Lease, Liability, to be Paid, Year Four Prepaid Inventory Costs Prepaid Inventory Costs, Policy [Policy Text Block] Prepaid Inventory Costs, Policy Change in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Operating Loss Carryforwards [Table] Operating Loss Carryforwards [Table] Revenue interest rate which will take effect if annual net sales equals or exceeds the Sales Threshold by December 31, 2021 Revenue Interest Rate, Tier Two The Revenue Interest Rate which will take effect if annual net sales equal or exceed $350.0 million by December 31, 2021. Option to purchase additional shares (in shares) Sale of Stock, Underwriter Option, Number Of Shares Sale of Stock, Underwriter Option, Number Of Shares Entity Address, City or Town Entity Address, City or Town Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount RSUs Restricted Stock Units (RSUs) [Member] Statement of Income Location, Balance [Domain] Statement of Income Location, Balance [Domain] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Quarterly principal payment rate after four years Debt Instrument, Quarterly Principal Rate After Four Years Debt Instrument, Quarterly Principal Rate After Four Years Aggregate consideration for the transaction Business Combination, Consideration Transferred Entity Emerging Growth Company Entity Emerging Growth Company 2028 Long-Term Debt, Maturity, Year Three Outstanding at the beginning of period (in shares) Outstanding at the end of the period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Debt issuance costs Debt Issuance Costs, Net Securities Purchase Agreement Securities Purchase Agreement [Member] Securities Purchase Agreement Basis spread on make-whole premium Debt Instrument, Basis Spread On Make-Whole Premium In Next Two Years Debt Instrument, Basis Spread On Make-Whole Premium In Next Two Years Sale of Future Royalties Sale Of Future Royalties Disclosure [Text Block] Sale Of Future Royalties Disclosure Number of notices received from pharmaceutical companies Abbreviated New Drug Application Litigation, Number Of Notices Received Abbreviated New Drug Application Litigation, Number Of Notices Received Shares issued (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Other prepaid and current assets Prepaid Expense and Other Assets, Current Number of RSUs Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Restatement Determination Date Restatement Determination Date Provision for taxes on income Provision for taxes on income Income Tax Expense (Benefit) Scheduled trading days Debt Instrument, Redemption Option, Period Prior To Maturity Date, Scheduled Trading Days Debt Instrument, Redemption Option, Period Prior To Maturity Date, Scheduled Trading Days Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Property and equipment, gross Property, Plant and Equipment, Gross Proceeds from royalty sale liability Proceeds From Royalty Sale Liability, Net Of Issuance Costs Proceeds From Royalty Sale Liability, Net Of Issuance Costs Commitment Offering Commitment Offering [Member] Commitment Offering Number of customers Concentration Risk, Number of Customers The number of the Company's customers. Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] U.S federal Income Tax Paid, Federal, after Refund Received All Trading Arrangements All Trading Arrangements [Member] Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Deferred tax liabilities: Deferred Tax Liabilities, Gross [Abstract] Outstanding and unvested at the beginning of period (in shares) Outstanding and unvested at the ending of period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Amortization expense, year two and thereafter Royalty Sale Liability, Capitalized Issuance Costs, Amortized Expense, Year Two And Thereafter Royalty Sale Liability, Capitalized Issuance Costs, Amortized Expense, Year Two And Thereafter Convertible notes, net of issuance costs Convertible Notes Payable, Noncurrent Unrecognized stock-based compensation expense, options Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Estimated useful lives Property, Plant and Equipment, Useful Life Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Subsequent Event Subsequent Event [Member] Schedule of Weighted-Average Assumptions Used to Compute the Stock-Based Compensation Costs for the Stock Options Granted to Employees Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Duration of offering periods Employee Stock Purchase Plan, Duration of Offering Period The duration of offering periods in which employees may purchase stock, , in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] PEO Total Compensation Amount PEO Total Compensation Amount Long-term Debt, Type [Axis] Long-Term Debt, Type [Axis] Depreciation expense Depreciation Vested and expected to vest (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Money market funds Money Market Funds [Member] Other Accrued Liabilities Other Liabilities Disclosure [Text Block] Equity Components [Axis] Equity Components [Axis] Property and Equipment Property, Plant and Equipment [Line Items] Convertible Debt Convertible Debt [Member] Vesting of restricted stock units Stock Issued During Period, Value, Restricted Stock Award, Gross Increase in common stock shares reserved and available for issuance, as a percentage of common stock shares outstanding Share Based Compensation Arrangement by Share Based Payment Award, Number of Additional Shares Authorized as Percentage of Shares Issued and Outstanding Represents the annual increase in number of shares of stock reserved and available for issuance under a share-based award plan by the specified percentage of the number of shares of stock issued and outstanding on the immediately preceding the end date. Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Trade Accounts Receivable Trade Accounts Receivable [Member] Weighted-Average Remaining Contractual Term (Years) Share Based Compensation Arrangement by Share Based Payment Award Options Weighted Average Remaining Contractual Term [Abstract] Upfront cash payment Up-Front Payment The amount of up-front payment paid. Product Product [Member] Number of reportable segments Number of Reportable Segments Deferred tax assets Components of Deferred Tax Assets [Abstract] Entity Address, State or Province Entity Address, State or Province Antidilutive Security, Excluded EPS Calculation [Table] Antidilutive Security, Excluded EPS Calculation [Table] Total current liabilities Liabilities, Current Vesting of restricted stock units (in shares) Stock Issued During Period, Shares, Restricted Stock Award, Gross Individual: Individual [Axis] Contributions to the 401(k) Plan Defined Contribution Plan, Cost Income Tax Jurisdiction [Domain] Income Tax Jurisdiction [Domain] Document Annual Report Document Annual Report Research and development Research and Development Expense [Member] Cardiovascular Risk Outcome Less than Twenty Percent Cardiovascular Risk Outcome Greater Than Fifteen But Less Than Twenty Percent [Member] Cardiovascular Risk Outcome Greater Than Fifteen But Less Than Twenty Percent Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Entity Interactive Data Current Entity Interactive Data Current Cash payment to the Company Cash Payment to be Received upon First Commercial Sales The amount of cash payment to the Company upon the completion of the Nustendi Marketing Authorization Applications Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Compensation Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Amount Federal and state operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards Property, Plant and Equipment, Type [Axis] Long-Lived Tangible Asset [Axis] Period from cessation of employment within which options expire if not exercised Share Based Compensation Arrangement by Share Based Payment Award Period from Cessation of Employment within which Options Expire if Not Exercised Represents the period from cessation of employment within which options expire if not exercised. Type Of Risk[Axis] Type Of Risk [Axis] Type Of Risk One time partial call One Time Partial Call One Time Partial Call Convertible notes, net of issuance costs Convertible Notes Payable, Current Accrued interest Interest Payable, Current Customer [Domain] Customer [Domain] Entity Central Index Key Entity Central Index Key PEO Name PEO Name Debt instrument, convertible, conversion price (in dollars per share) Debt Instrument, Convertible, Conversion Price Schedule of Estimated Future Principal Payments Schedule of Maturities of Long-Term Debt [Table Text Block] Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Schedule of Segment Reporting Information, by Segment [Table] Schedule of Segment Reporting Information, by Segment [Table] Deferred revenue from collaborations Contract with Customer, Liability, Current Exercise price (in dollars per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Prepaids and other assets Increase (Decrease) in Prepaid Expense and Other Assets RIPA Amendment To The Security Agreement And Waiver RIPA Amendment To The Security Agreement And Waiver [Member] RIPA Amendment To The Security Agreement And Waiver Work in process Inventory, Work in Process, Net of Reserves Convertible Senior Notes Due 2025 Convertible Senior Notes Due 2025 [Member] Convertible Senior Notes Due 2025 Exercise Price Award Exercise Price Entity Filer Category Entity Filer Category Class of Stock [Domain] Class of Stock [Domain] Unrecognized stock-based compensation expense Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount Federal income tax (benefit) at statutory rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Subsequent Event Type [Axis] Subsequent Event Type [Axis] Percentage of risk reduction Percentage Of Risk Reduction Percentage Of Risk Reduction Revenue interest liability, beginning balance Revenue interest liability, ending balance Revenue Interest Liability Represents the current and non-current portion of the Revenue Interest Liability. Interest expense recognized Revenue Interest Liability, Increase for Interest Expense Recognized The amount of increase in the revenue interest liability attributable to interest expense recognized during the period. Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Statement of Financial Position Location, Balance [Axis] Statement of Financial Position Location, Balance [Axis] Other accrued liabilities Total other accrued liabilities ​Accrued Liabilities And Employee-Related Liabilities, Current ​Accrued Liabilities And Employee-Related Liabilities, Current Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Entity Address, Address Line One Entity Address, Address Line One Accumulated Other Comprehensive Loss AOCI Attributable to Parent [Member] Meals and entertainment Effective Income Tax Rate Reconciliation, Nondeductible Expense, Meals and Entertainment, Percent Trailing number of months sales must be at or above milestone amount Trailing Number Of Months Sales Must Be At Or Above Milestone Amount The trailing number of months sales must be at or above the milestone amount. Fair Value as of Grant Date Award Grant Date Fair Value Proceeds from exercise of warrants Proceeds from Warrant Exercises Net operating loss carryforwards Operating Loss Carryforwards Changes in unrecognized tax benefits Effective Income Tax Rate Reconciliation, Tax Contingency, Amount Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Accrued legal fees Accrued Legal Fees, Current Accrued Legal Fees, Current Net deferred tax assets, before valuation allowance Deferred Tax Assets, Net Of Deferred Tax Liabilities, Before Valuation Allowance Deferred Tax Assets, Net Of Deferred Tax Liabilities, Before Valuation Allowance Forfeited or expired (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Accrued variable consideration Deferred Tax Assets, Accrued Variable Consideration Deferred Tax Assets, Accrued Variable Consideration Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Counterparty Name [Domain] Counterparty Name [Domain] 2027 Lessee, Operating Lease, Liability, to be Paid, Year Two Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Accrued interest receivables Accrued Investment Income Receivable Title Trading Arrangement, Individual Title Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount 2017 Inducement Equity Plan Inducement Equity Plan Plan2017 [Member] Represents information pertaining to the 2017 Inducement Equity Plan. Percentage of royalties to be received on the net sales Percentage of Royalties to be Received on Net Sales The percentage of royalties to be received on net sales. Non-PEO NEO Non-PEO NEO [Member] Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Allowance for credit losses Debt Securities, Available-for-Sale, Allowance for Credit Loss Vesting of ESPP Shares Stock Issued During Period, Value, Employee Stock Purchase Plan Royalty Revenue From DSE And Sale Of Bulk Tablets And Milestones Received Royalty Revenue From DSE And Sale Of Bulk Tablets And Milestones Received [Member] Royalty Revenue From DSE And Sale Of Bulk Tablets And Milestones Received Sale of Stock [Axis] Sale of Stock [Axis] Gross Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Equity Award [Domain] Award Type [Domain] 2026 Lessee, Operating Lease, Liability, to be Paid, Year One Warrants exercised (in shares) Class of Warrant or Right, Exercised Class of Warrant or Right, Exercised Royalties recognized and settled to Purchaser Royalty Sale Liability, Decrease for Royalties Recognized Royalty Sale Liability, Decrease for Royalties Recognized Equity Awards Adjustments Equity Awards Adjustments [Member] Leasehold improvements Leasehold Improvements [Member] Advertising expense Advertising Expense Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block] Royalty sale liability Beginning balance of royalty sale liability Ending balance of royalty sale liability on June 27, 2024 Royalty Sale Liability Royalty Sale Liability Compensation Amount Outstanding Recovery Compensation Amount Floor price (in dollars per share) Debt Instrument, Exchange Agreement, Conversion, Weighted Average Price Per Share Floor Debt Instrument, Exchange Agreement, Conversion, Weighted Average Price Per Share Floor Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Certificates of deposit Certificates of Deposit [Member] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Type Of Risk [Domain] Type Of Risk [Domain] Type Of Event [Domain] Prepaid inventory costs Prepaid Inventory Costs Prepaid Inventory Costs MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Employee Stock Shares issuable related to the ESPP Employee Stock [Member] Revenues: Revenues [Abstract] Documents Incorporated by Reference Documents Incorporated by Reference [Text Block] Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax 2026 Long-Term Debt, Maturity, Year One Financial Instruments [Domain] Financial Instruments [Domain] Total deferred tax liabilities Deferred Tax Liabilities, Gross 2030 Long-Term Debt, Maturity, Year Five Performance Shares Unvested PBRSUs Performance Shares [Member] Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Number of finance leases Number Of Finance Leases, Not Yet Commenced Number Of Finance Leases, Not Yet Commenced Automobile leases and IT equipment leases Operating Leases I T Equipment Leases And Automobile Leases [Member] Represents information pertaining to operating leases for automobiles and IT equipment. Estimated offering expenses Payments for Commissions Inventories, net Total Inventory Inventory, Net Threshold ratio of purchase price Sale Of Future Royalties, Threshold Purchase Price Multiplier Sale Of Future Royalties, Threshold Purchase Price Multiplier Minimum Minimum [Member] Company Selected Measure Name Company Selected Measure Name Revenue Interest Purchase Agreement (RIPA) Revenue Interest Purchase Agreement [Member] Represents the information pertaining to revenue interest purchase agreement ("RIPA"). Repurchase consideration Repurchase of Revenue Interests Payments For Repurchase Of Revenue Interests Payments For Repurchase Of Revenue Interests Summary of Significant Accounting Policies [Line Items] Summary of Significant Accounting Policies [Line Items] Summary of Significant Accounting Policies Cost of Goods Sold Cost of Goods and Service [Policy Text Block] Liability From Sale Of Future Revenues [Roll Forward] Liability From Sale Of Future Revenues [Roll Forward] Liability From Sale Of Future Revenues Debt Debt Disclosure [Text Block] Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Accounts payable Accounts Payable, Current Cash paid for the amounts included in the measurement of lease liabilities Operating Lease, Payments Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Operating loss carryforwards, subject to expiration Operating Loss Carryforwards, Subject To Expiration Operating Loss Carryforwards, Subject To Expiration Weighted-average shares outstanding - diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Segment Reporting Segment Reporting, Policy [Policy Text Block] Stock-based compensation expense related to stock options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Entity Small Business Entity Small Business Selling, general and administrative Selling and Marketing Expense [Member] Payment of issuance costs Payments of stock issuance costs Payments of Stock Issuance Costs Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding State Current State and Local Tax Expense (Benefit) Document Transition Report Document Transition Report Additional consideration per amended warrant (in dollars per share) Class of Warrant or Right, Exercise Price of Warrants or Rights, Additional Consideration Class of Warrant or Right, Exercise Price of Warrants or Rights, Additional Consideration Underlying Securities Award Underlying Securities Amount Equity Component [Domain] Equity Component [Domain] Document Period End Date Document Period End Date Income Taxes Income Tax Disclosure [Text Block] Common stock Common Class A [Member] Proceeds from credit agreement, net of issuance costs Proceeds from Lines of Credit HLS Therapeutics HLS Therapeutics [Member] HLS Therapeutics Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Document Type Document Type Level 3 Fair Value, Inputs, Level 3 [Member] Net Loss Per Common Share Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name Loss Contingencies [Table] Loss Contingencies [Table] Additional paid-in capital Additional Paid in Capital Specified net revenue Specified Net Revenue Threshold Triggering Deposit In Blocked Account Maximum Amount of Net Revenue To Qualify For Deposit In Blocked Account Exercise of warrants Stock Issued During Period, Value, Warrant Exercises Stock Issued During Period, Value, Warrant Exercises Product and Service [Axis] Product and Service [Axis] Total Revenues Revenue from Contract with Customer, Excluding Assessed Tax Vested and expected to vest (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Royalty sale liability Royalty Sale Liability, Non Current Royalty Sale Liability, Non Current Total current assets Assets, Current Supplemental balance sheet information related to leases Assets and Liabilities, Lessee [Abstract] Statistical Measurement [Axis] Statistical Measurement [Axis] Forfeited (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Weighted Average Exercise Price Common Stock And Accompanying Warrant Common Stock And Accompanying Warrant [Member] Common Stock And Accompanying Warrant Minimum liquidity Debt Instrument, Covenant, Minimum Liquidity Debt Instrument, Covenant, Minimum Liquidity Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Accounts Receivable Risks Accounts Receivable Risks [Member] Accounts Receivable Risks Corstasis Therapeutics Inc. Corstasis Therapeutics Inc. [Member] Corstasis Therapeutics Inc. Pre-tax intrinsic value of stock options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Neopharm Neopharm [Member] Neopharm Other comprehensive gain Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Current liabilities: Liabilities, Current [Abstract] R&D tax credits, net of reserves Deferred Tax Assets, Tax Credit Carryforwards, Research Total operating expenses Operating Expenses Second milestone payment Settlement Agreement Aggregate Second Milestone Payment From Partner Settlement Agreement Aggregate Second Milestone Payment From Partner Level 1 Fair Value, Inputs, Level 1 [Member] Beginning balance (in shares) Ending balance (in shares) Shares, Outstanding Liability Related to the Revenue Interest Purchase Agreement Liability Related to the Revenue Interest Purchase Agreement No definition. Net loss per common share - diluted (in dollars per share) Earnings Per Share, Diluted Other accrued liabilities Increase (Decrease) in Other Accrued Liabilities Accounts receivable, net Accounts Receivable, after Allowance for Credit Loss, Current Reclassification out of Accumulated Other Comprehensive Income [Axis] Reclassification out of Accumulated Other Comprehensive Income [Axis] Issued stock (in shares) Sale of Stock, Number of Shares Issued in Transaction Treasury stock (in shares) Treasury Stock, Common, Shares Percentage of invested capital received by December 31, 2024, to qualify for second reduced revenue interest rate Percentage of Invested Capital Received By December 31, 2024, To Qualify For Second Reduced Revenue Interest Rate Percentage of invested capital received by December 31, 2024, to qualify for second reduced revenue interest rate. U.S. state and local Income Tax Paid, State and Local, after Refund Received The Company and Basis of Presentation Business Description and Basis of Presentation [Text Block] Auditor Location Auditor Location 2013 Stock Option and Incentive Plan Stock Option And Incentive Plan2013 [Member] Represents information pertaining to 2013 Stock Option and Incentive Plan. 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Milestone payment aggregate amount Business Combination, Contingent Consideration, Range of Outcomes, Maximum, Amount Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Accounts receivable Increase (Decrease) in Accounts Receivable Inventories, net Inventory, Policy [Policy Text Block] Entity Current Reporting Status Entity Current Reporting Status Repurchase or principal payment of revenue interest liability Payments For Repurchase Of Revenue Interest Liability Payments For Repurchase Of Revenue Interest Liability Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Federal income tax (benefit) at statutory rate Effective Income Tax Rate Reconciliation at Federal Statutory Income Tax Rate, Amount Financial Instrument [Axis] Financial Instrument [Axis] Deferred tax assets: Deferred Tax Assets, Gross [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Noncash Item [Abstract] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Executive Category: Executive Category [Axis] Compensation Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent State and local income taxes, net of federal income tax effect Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent Amount of subsequent installment, subject to achievement of Sales Threshold Amount of Subsequent Installment, Subject to Achievement of Sales Threshold The amount of the subsequent installment which is subject to the achievement of the Sales Threshold as defined in the Revenue Interest Purchase Agreement. 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Percentage of revenue interests payment on which agreement terminates after third anniversary Percentage Of Revenue Interests Payment on Which Agreement Terminates Percentage of revenue interests payment on which agreement terminates. Property, Plant and Equipment, Type [Domain] Long-Lived Tangible Asset [Domain] Oberland Eiger Iii Sa Llc [Member] Represents the information pertaining to revenue interest purchase agreement ("RIPA") with Oberland. 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Changes in unrecognized tax benefits Effective Income Tax Rate Reconciliation, Tax Contingency, Percent Subsidiary or Equity Method Investee, Sale of Stock, Type [Table] Subsidiary or Equity Method Investee, Sale of Stock, Type [Table] Total deferred tax assets Deferred Tax Assets, Gross If-converted value in excess of principal value Debt Instrument, Convertible, If-converted Value in Excess of Principal Short-term debt Short-Term Debt Inventory Disclosure [Abstract] Debt instrument, convertible, threshold percentage of stock price trigger Debt Instrument, Convertible, Threshold Percentage of Stock Price Trigger Capitalized issuance costs Royalty Sale Liability, Capitalized Issuance Costs Royalty Sale Liability, Capitalized Issuance Costs Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Research and Development Research and Development Expense, Policy [Policy Text Block] Total stock compensation expense Share-Based Payment Arrangement, Expense Cumulative Purchaser Payment adjustment Revenue Interests Payment On Which Agreement Terminates Revenue Interests Payment On Which Agreement Terminates Current assets: Assets, Current [Abstract] Total liabilities and stockholders' deficit Liabilities and Equity Net Income (Loss) Per Common Share Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Number of Options Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Concentration Risk Benchmark [Axis] Concentration Risk Benchmark [Axis] Percent acquired Sale Of Future Royalties, Percentage Royalty Interests Acquired Sale Of Future Royalties, Percentage Royalty Interests Acquired Collaboration Revenue Collaboration Revenue [Member] Represents the information pertaining to collaboration revenue. Accounting Policies [Abstract] Accounting Policies [Abstract] Schedule of Future Maturities of Operating Lease Liabilities Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Concentration Risk Type [Domain] Concentration Risk Type [Domain] Treasury Stock Treasury Stock, Common [Member] Meals and entertainment Effective Income Tax Rate Reconciliation, Nondeductible Expense, Meals and Entertainment, Amount Fair value of shares vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value Pay vs Performance Disclosure [Line Items] Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Total Total lease obligations under operating leases Operating Lease, Liability Number of additional operating leases Number Of Additional Operating Leases Number Of Additional Operating Leases Milestone payments related to total net sales achievements Future Payment Milestone, Sales Milestones The total amount of potential future payments related to total net sales achievements for Otsuka in Japan. Amount of subsequent installment, subject to regulatory approval Amount of Subsequent Installment, Subject to Regulatory Approval The amount of the subsequent installment which is subject to regulatory approval. 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Common stock purchasable under prefunded warrants (in shares) Common Stock Purchasable Under Prefunded Warrants Common Stock Purchasable Under Prefunded Warrants Milestone payment upon JNDA Approval in the Otsuka Territory Future Payment Milestone, First Submission of Japanese New Drug Application, Otsuka Territory The amount of a potential future payment which becomes due with the submission of a Japanese New Drug Application (JNDA). in the Otsuka Territory. 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Product and Service [Domain] Product and Service [Domain] Customer Concentration Risk Customer Concentration Risk [Member] Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Income Tax Paid, by Individual Jurisdiction [Table] Income Tax Paid, by Individual Jurisdiction [Table] City Area Code City Area Code Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] Prepayment premium during year four Debt Instrument, Prepayment Premium, Year Four Debt Instrument, Prepayment Premium, Year Four Summary of Revenue Interest Liability Activity Schedule of Revenue Interest Liability [Table Text Block] Tabular disclosure of information pertaining to the revenue interest liability. Purchase discount Employee Stock Purchase Plan, Percentage Discount on Shares The discount at which shares may be purchased under the employee stock purchase plan, calculated as a stated percentage of the lesser of the closing price of the Company's common stock on the NASDAQ Global Select Market (i) on the first trading day of the offering period or (ii) the last day of any offering period. 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Ltd Daiichi Sankyo Co. Ltd [Member] Daiichi Sankyo Co. 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Potential additional future payments Aggregate Amount of Potential Future Revenue, Total Development and Sales Milestones The aggregate amount of potential future revenue which may be received under the terms of the agreement conditional upon achievement of specified total development and sales milestones. 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These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Arrangement Duration Trading Arrangement Duration Otsuka Pharmaceutical Co Ltd Otsuka Pharmaceutical Co Ltd [Member] Represents information pertaining to Otsuka Pharmaceutical Co, Ltd. Computer equipment Computer Equipment [Member] Collaborations with Third Parties Collaborations with Third Parties n/a Local Phone Number Local Phone Number Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Arrangements and Non-arrangement Transactions [Domain] Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Stock Compensation Share-Based Payment Arrangement [Text Block] Incentive Stock Option And Restricted Stock Plan 2022, 2017 And 2013 Incentive Stock Option And Restricted Stock Plan 2022, 2017 And 2013 [Member] Incentive Stock Option And Restricted Stock Plan 2022, 2017 And 2013 Assets Assets [Abstract] Underlying Security Market Price Change Underlying Security Market Price Change, Percent Warrants expired (in shares) Class Of Warrant Or Right, Expired Class Of Warrant Or Right, Expired Debt Instrument [Axis] Debt Instrument [Axis] Forfeited or expired (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Employee Benefit Plan Retirement Benefits [Text Block] Fair Value Measurements Fair Value Disclosures [Text Block] Loss on extinguishment of debt and exchange transaction Non-cash loss on extinguishment of debt and exchange transaction Loss on extinguishment of debt Gain (Loss) on Extinguishment of Debt Stockholders’ deficit: Equity, Attributable to Parent [Abstract] Vesting percentage on the first anniversary of the option grant Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Interest rate percentage Debt Instrument, Interest Rate, Stated Percentage Operating lease liabilities Operating lease liabilities (long-term) Operating Lease, Liability, Noncurrent Entity Voluntary Filers Entity Voluntary Filers Property and Equipment, Net Property, Plant and Equipment [Abstract] Entity Registrant Name Entity Registrant Name Collaborative Arrangement Collaborative Arrangement [Member] Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Convertible Senior Notes Due 2030 Convertible Senior Notes Due 2030 [Member] Convertible Senior Notes Due 2030 State and local - Other State and Local Tax Jurisdiction, Other [Member] Issuance costs to additional paid in capital Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Total assets at fair value Assets, Fair Value Disclosure Payments on revenue interest liability Revenue interest payments Payments From Revenue Interest Purchase Agreement The cash outflow from a revenue interest purchase agreement. 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Reclassification out of Accumulated Other Comprehensive Income Reclassification out of Accumulated Other Comprehensive Income [Member] Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents [Abstract] Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract] Principal Executive Office Principal Executive Office [Member] Principal Executive Office Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Leases Lessee, Lease, Description [Line Items] Common stock exchanged (in shares) Debt Conversion, Converted Instrument, Shares Issued Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Stock Option And Incentive Plan 2022 Stock Option And Incentive Plan 2022 [Member] Stock Option And Incentive Plan 2022 Accrued clinical development costs Accrued Clinical Development Costs, Current Carrying value as of the balance sheet date of obligations incurred through that date and payable for clinical development. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle, if longer). Original issue discount percentage Debt Instrument, Original Discount (Premium), Percentage Debt Instrument, Original Discount (Premium), Percentage Non-cash right of use asset Non Cash Right Of Use Asset Represents the difference between the lease asset and the lease liability. 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Other income, net Unrealized gains (losses) Other Nonoperating Income (Expense) Statement [Table] Statement [Table] Total deferred income taxes Deferred Income Tax Expense (Benefit) Financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Permanent items Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent Revenue Benchmark Revenue Benchmark [Member] Non-cash interest expense related to the royalty sale liability Non Cash Interest Expense Related To Royalty Sale Liability Non Cash Interest Expense Related To Royalty Sale Liability All Adjustments to Compensation All Adjustments to Compensation [Member] Amendment Flag Amendment Flag Price per share (in dollars per share) Sale of Stock, Price Per Share Number of commons stock shares available for issuance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Treasury stock, at cost; 1,994,198 shares at December 31, 2025 and December 31, 2024 Treasury Stock, Common, Value Termination Date Trading Arrangement Termination Date Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Raw materials Inventory, Raw Materials, Net of Reserves Payment to be received upon milestone Cash Payment To Be Received Upon Certain Commercial Milestones Cash Payment To Be Received Upon Certain Commercial Milestones Weighted average discount rate Operating Lease, Weighted Average Discount Rate, Percent Summary of Activity Relating to the Company's Options to Purchase Common Stock Share-Based Payment Arrangement, Option, Activity [Table Text Block] Income tax penalties and interest expense Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued Weighted-average shares outstanding - basic (in shares) Weighted Average Number of Shares Outstanding, Basic Unrecognized tax benefits that would impact effective tax rate Unrecognized Tax Benefits that Would Impact Effective Tax Rate Exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Convertible Senior Notes Due 2030, Subscription Transactions Convertible Senior Notes Due 2030, Subscription Transactions [Member] Convertible Senior Notes Due 2030, Subscription Transactions Subsequent Events [Abstract] Segment Reporting [Abstract] Debt Disclosure [Abstract] Scenario [Domain] Scenario [Domain] Period for which remainder of grant amount will vest on the first day of each calendar quarter Share Based Compensation Arrangement by Share Based Payment Award, Award Vesting Period for Remaining Grant Amount Represents the period which an employee's right to exercise an award is no longer contingent on satisfaction of either a service condition, market condition or a performance condition for remaining grant amount. Remaining unamortized discount Debt Instrument, Unamortized Discount Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Stock compensation Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Cash Equivalents Cash and Cash Equivalents Disclosure [Text Block] Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Use of Estimates Use of Estimates, Policy [Policy Text Block] Subsequent Event Subsequent Events [Text Block] Insider Trading Arrangements [Line Items] Non-cash interest expense related to the revenue interest liability Non Cash Interest Expense Related to Revenue Interest Liability The amount of non-cash expense included in interest expense associated with the revenue liability. 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